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PNQ 103 from Advinus for the potential treatment of COPD & sickle cell...
PNQ 103 STRUCTURE COMING………… for the potential treatment of COPD & sickle cell disease (SCD) Adenosine A2b receptor antagonist Advinus Therapeutics Ltd KEEP WATCHING THIS POST………. PNQ-103 is a...
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Fluorofenidone
Fluorofenidone 1- (3-fluorophenyl) -5-methyl – 2 (1H) pyridone 2(1H)-Pyridinone, 1-(3-fluorophenyl)-5-methyl- 1- (3_ fluorophenyl) -5_ methylpyridine _2 (IH) – one C12 H10 F N O, 203.2123...
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Merck’s Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP)
Indoline 7 as in ACS MEDCHEM LETTERS, DOI: 10.1021/acsmedchemlett.5b00404 and eg 10 as in WO2015054088 (2R)- 1,1,1 -trifluoro-3-(3-(3-(trifluoromethoxy)benzyl)-3-(3-...
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Preclinical characterization of substituted...
MW 422.79, MF C18 H14 Cl F3 N6 O cas 1627748-32-6 1,2,4-Triazolo[4,3-a]pyrazin-8(5H)-one,...
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BMS 955829
(4R,5R)-5-(2,5-difluorophenyl)-4-(5-(phenylethynyl)pyridin-3-yl)oxazolidin-2-one (4R,5R)-5(2,5-Difluorophenyl)-4-(5-(phenylethynyl)-3-pyridinyl)-1,3-oxazolidin-2-one (4R,5R)-5-(2,5-difluorophenyl)-...
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Shanghai Hengrui’s potent inhibitors of Human Uric Acid Transporter 1 (hURAT1)
MF C 1 4 H 1 2 BrNO 2 S MW 338.21958 g / mol 1- (6-bromoquinolin-4-yl) sulfanylcyclobutane-1-carboxylic acid CAS…….1638327-48-6 Cyclobutanecarboxylic acid, 1-[(6-bromo-4-quinolinyl)thio]-...
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SKLB 1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl,
SKLB 1028 IND Filed A multi-targeted inhibitor potentially for the treatment of leukemia and non small cell lung cancer. SKLB-1028 Si Chuan University, 四川大学 CAS 1350544-93-2...
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Avoralstat
Avoralstat, BCX4161, CAS 918407-35-9 UNII: UX17773O15 513.5513, C28-H27-N5-O5 2-Pyridinecarboxylic acid,...
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Tianagliflozin IND filed by Tianjin Institute of Pharmaceutical research
Tianagliflozin, taigeliejing, 6-deoxydapagliflozin Molecular Formula: C21H25ClO5 Molecular Weight: 392.8732 g/mol IND Filing…Tianjin Institute of Pharmaceutical research Tianjin Institute Of...
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IACS -9571
IACS-9571 TRIM24/BRPF1 bromodomain inhibitor IACS-9571; IACS 9571; IACS9571. Molecular Formula: C32H42N4O8S Molecular Weight: 642.76288 g/mol...
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Letermovir, AIC 246
Letermovir, MK 8828, AIC 246 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid CAS 917389-32-3 Letermovir; UNII-1H09Y5WO1F;...
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PDE4 Inhibitors, Boehringer Ingelheim Pharmaceuticals
R CONF SHOWN BI ? (R)-2-(4-(4-Chlorophenoxy)piperidin-1-yl)-4-((tetrahydro-2H-pyran-4-yl)amino)-6,7-dihydrothieno[3,2-d]pyrimidine 5-Oxide C22 H27 Cl N4 O3 S, 462.99 CAS 1910076-27-5...
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MK 8718
MK 8718 Cas 1582729-24-5 (free base); 1582732-29-3 (HCl). MF: C30H30ClF6N5O4 MW: 673.1891 INNOVATOR Merck Sharp & Dohme Corp., Merck Canada Inc....
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MK-7145
MK-7145, cas 1255204-84-2 1(3H)-Isobenzofuranone, 5,5′-(1,4-piperazinediylbis((1R)-1-hydroxy-2,1-ethanediyl))bis(4-methyl- MF C26 H30 N2 O6, Molecular Weight 466.53 1(3H)-Isobenzofuranone,...
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Quisapride Hydrochloride
Quisapride Hydrochloride (R) – quinuclidine-3-5 – ((S) -2 – (( 4 – amino-5-chloro-2-ethoxy benzoylamino) methyl) morpholino) hexanoate IND Filed china A 5-HT4 agonist potentially for the treatment of...
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Antimycobacterial Agents
Styryl Hydrazine Thiazole Hybrids Will be updated………kindly email amcrasto@gmail.com DATA ABOUT Dehydrozingerone Dehydrozingerone; Feruloylmethane; 1080-12-2;...
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CFI-402257
CFI-402257 N-cyclopropyl-4-(7-((((1s,3s)-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(pyridin-2-yloxy)pyrazolo[1,5-a]pyridin-3-yl)-2-methylbenzamide N-cyclopropyl-4-(7-( (((Is,...
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SETIPIPRANT
Setipiprant, KYTH-105 CAS 866460-33-5 2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid...
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CCT 245737
CCT 245737 CAS:1489389-18-5 M.Wt: 379.34 Formula: C16H16F3N7O 2-Pyrazinecarbonitrile, 5-[[4-[[(2R)-2-morpholinylmethyl]amino]-5-(trifluoromethyl)-2-pyridinyl]amino]-...
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GSK 6853
GSK 6853 CAS 1910124-24-1 C22 H27 N5 O3, 409.48 Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxy- (R)-N-(1 ,3-...
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